The upcoming fixtures for Round 2 are listed below. These matches are to take place on Saturday 26th October.
 | Appley Bridge | v | Cherrybrook |  |
 | Castle FC | v | Hoole United |  |
 | Sir Tom Finney | v | Marsh United |  |
 | Burscough FC Reserves | v | Astley FC |  |
 | Wyre Villa Reserves | v | AFC Ainsdale |  |